High Performance Health Podcasts - 364

Bitesize:
The Benefits and Risks(!) of NAD
with Nichola Conlon

Angela welcomes Nichola Conlon to talk about the critical molecule NAD (Nicotinamide Adenine Dinucleotide) and its importance for the human body.

Nichola provides a comprehensive overview of NAD, highlighting its crucial roles in energy production within cells and as a signaling molecule for cellular maintenance and repair. Angela and Nichola also look into how NAD levels decline with age, impacting energy levels and cellular health, ultimately contributing to the aging process

Description

Angela welcomes Nichola Conlon to talk about the critical molecule NAD (Nicotinamide Adenine Dinucleotide) and its importance for the human body.

Nichola provides a comprehensive overview of NAD, highlighting its crucial roles in energy production within cells and as a signaling molecule for cellular maintenance and repair. Angela and Nichola also look into how NAD levels decline with age, impacting energy levels and cellular health, ultimately contributing to the aging process

Key Takeaways

NAD, or nicotinamide adenine dinucleotide, is a crucial molecule for energy production in cells and acts as a signaling molecule for cellular maintenance and repair.
NAD levels decline with age, starting from birth, and this decline is linked to reduced energy levels and impaired cellular maintenance and repair, contributing to the aging process.
Intermittent fasting, calorie restriction, and exercise are ways to positively impact NAD levels by creating an energy stress that activates the AMPK pathway, leading to increased NAD production.
High-intensity interval training and fasting in a fasted state can further upregulate the AMPK pathway, enhancing the body's ability to produce NAD.
The salvage pathway in cells is responsible for recycling NAD breakdown products, primarily nicotinamide, back into usable NAD. However, this pathway becomes dysregulated with age due to a decline in the enzyme NAMPT, leading to decreased NAD levels in older cells.

Best Moments

"NAD, I sometimes refer to it as probably the most important molecule that you've never heard of." 

"From research that's been done, it seems like it declines from birth. So by the time you're age 20, you've kind of got half the amounts of NAD that you had when you were born." 

"I think what's known is that any level of fasting really is going to start to actually increase your NAD levels."

"So all the beneficial effects of exercise, fasting, et cetera, are happening because they're increasing the ability of our cells to use this salvage pathway."

High
Performance
Health

The High-Performance Health Podcast is all about optimising your body, mind and lifestyle for high performance.

Packed full of actionable insights, strategies, bio hacks, lifestyle hacks, mindset strategies and expert performance advice, Angela Foster is on a mission to optimise your human potential. Featuring interviews with some of the top experts on the planet in the fields of health, performance and business, this show aims to inspire, educate and empower you to live an energetic, healthful and limitless life.

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About Angela

Angela is a Nutritionist, Health and Performance Coach. She is also the Founder and CEO of My DNA Edge, an Exclusive Private Membership Site giving individuals the tools and bio hacks needed to optimise their genetic expression for optimal health and performance.

 
Angela believes that we can truly have it all and has spent the last 5 years researching the habits and routines of high performers, uncovering age-old secrets, time-honoured holistic practices and modern science to create a blueprint for Optimal Human Performance.

Angela is a functional nutrition practitioner and executive health & performance coach.

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