High Performance Health Podcasts -468

The Creatine Masterclass: Why This One Supplement Could Change Everything for Women’s Health | Darren Candow  

What if creatine isn’t just for bodybuilders—but a potent, research-backed tool for women’s health, performance, and longevity? In this powerhouse episode, Angela sits down with Darren Candow, a leading expert on creatine and Professor and Director of the Aging Muscle and Bone Health Laboratory at the University of Regina, Canada. Darren is also the Director of Research for the Athlete Health and Performance Initiative and past Associate Dean of Graduate Studies and Research in the Faculty of Kinesiology and Health Studies.

Description

What if creatine isn’t just for bodybuilders—but a potent, research-backed tool for women’s health, performance, and longevity? In this powerhouse episode, Angela sits down with Darren Candow, a leading expert on creatine and Professor and Director of the Aging Muscle and Bone Health Laboratory at the University of Regina, Canada. Darren is also the Director of Research for the Athlete Health and Performance Initiative and past Associate Dean of Graduate Studies and Research in the Faculty of Kinesiology and Health Studies. Together, they unpack the groundbreaking science behind one of the most misunderstood supplements. From brain energetics and mood stability to bone density, fat loss, and anti-aging, this is your comprehensive guide to creatine beyond the gym.

Angela and Darren explore the myths, the mechanisms, and the real-world applications of creatine—especially for women navigating perimenopause, high stress, and cognitive load. Whether you’re looking to train smarter, improve memory and sleep, or simply age with more energy and resilience, this masterclass will change the way you think about creatine forever.

Key Takeaways

Creatine for Cognitive Health: It crosses the blood-brain barrier slowly but significantly, especially under stress or sleep deprivation.
Dosage Evolution: 10g/day may be optimal for full muscle, brain, and bone saturation—especially in women.
Bone Health & Aging: Combined with resistance training, creatine may help preserve bone density, especially post-menopause.
Body Composition Benefits: Contrary to myth, creatine reduces body fat over time and improves lean mass, even in women.
Mental Health & Resilience: Early evidence shows potential benefits for depression, anxiety, and sleep quality.
Safer Than You Think: Creatine does not cause kidney issues or hair loss—these myths are finally being debunked with new data.
Emerging Synergies: Stacks with protein, collagen, or taurine may enhance its effects—especially for brain and recovery support.

Timestamps and Key Topics

0:00 – Introduction

3:33 – Creatine’s impact on fat loss, strength, and performance in women

7:31 – Recovery, overtraining & HRV: how creatine supports your nervous system

13:31 – Creatine for mood, mental health, and inflammation

18:36 – Bone health benefits in postmenopausal women

22:03 – Muscle breakdown: why women respond differently than men

31:25 – GAA, taurine & stacks that supercharge brain performance

36:28 – Brain fog, stress & cognition: creatine’s impact on energy and focus

47:43 – Creatine and sleep: timing, dosage, and recovery benefits

52:07 – The perimenopause trifecta: mood, metabolism, and muscle

55:13 – Final verdict: What dose actually works—and is it safe?

High
Performance
Health

The High-Performance Health Podcast is all about optimising your body, mind and lifestyle for high performance.

Packed full of actionable insights, strategies, bio hacks, lifestyle hacks, mindset strategies and expert performance advice, Angela Foster is on a mission to optimise your human potential. Featuring interviews with some of the top experts on the planet in the fields of health, performance and business, this show aims to inspire, educate and empower you to live an energetic, healthful and limitless life.

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Valuable Resources

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ABOUT THE GUEST

Darren G. Candow, Ph.D., CSEP-CEP, FISSN is a Professor and Director of the Aging Muscle and Bone Health Laboratory, Director of Research for the Athlete Health and Performance Initiative and past Associate Dean-Graduate Studies and Research in the Faculty of Kinesiology and Health Studies at the University of Regina, Canada. The overall objectives of Dr. Candow’s research program are to develop effective lifestyle interventions involving nutrition (primarily creatine monohydrate) and physical activity (resistance training) which have practical and clinical relevance for improving properties of muscle, bone and brain health/function. Dr. Candow has published > 150 peer-refereed journal manuscripts (h-index: 49, i10-index: 107), received > $2 million in research support, and supervised over 20 MSc and PhD students. In addition, Dr. Candow serves on the editorial review boards for the Journal of the International Society of Sports Nutrition; Nutrients; Frontiers; Advanced Exercise and Health Sciences; Scientific Reports; and Longevity and as a Scientific Advisor for AlzChem and Create. Dr. Candow is also a fellow of the International Society of Sports Nutrition and a Canadian Society for Exercise Physiology-Clinical Exercise Physiologist.

Darren G. Candow, PhD | CSEP-CEP | FISSN

Professor

Director-Aging Muscle and Bone Health Laboratory

Director of Research-Athlete Health and Performance Initiative

Faculty of Kinesiology & Health Studies

University of Regina

Google Scholar: https://scholar.google.ca/citations?hl=en&user=iUYFaeoAAAAJ&view_op=list_works&sortby=pubdate

Instagram: https://www.instagram.com/dr.darrencandow/?hl=en

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About Angela

Angela Foster is an award winning Nutritionist, Health & Performance Coach, Keynote Speaker and Host of The High Performance Health Podcast.

A former corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela regularly gives keynotes to large fitness, health and wellness events including the Health Optimisation summit, The Biohacker summit, Dragonfly live, Elevate Fitness conference and Gaia TV. She also delivers Health Optimisation and Performance Workshops to large multinational corporations and senior leaders with a strong focus on women’s health and burnout prevention.

Angela is also the creator of BioSyncing® a blueprint for high performing women who want to ditch burnout, harmonise their hormones and elevate their life.

Angela is a functional nutrition practitioner and executive health & performance coach.

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