[JESSICA KANE] (0:00 - 0:48)
Everyone on the planet's cellular health is damaged. As we age, our cell membrane starts to break down. When we look at the membrane of the cell, what's it doing?

The cell membrane is the commander in chief. It is the power centre. Perimenopause is actually a hormone signalling problem that is originating on the membrane.

So it's actually a cellular health problem first and a hormone problem second. What we need to do is really support our cellular health during this decline period. So many women complain about bloating.

We have low levels of a very important short-chain fatty acid called butyrate. It's a critically important molecule, particularly for inflammation. And it's a critically important short-chain fatty acid that people are just not getting enough of in today's world.

It has incredible benefits for metabolic health and blood sugar regulation, but it also naturally increases GLP-1.

[ANGELA FOSTER] (0:48 - 0:57)
This is something that perimenopausal women really struggle with, right? Is controlling their blood sugar, having food cravings, abdominal weight gain. It helps with cravings and things like that.

[JESSICA KANE] (1:00 - 1:03)
Should we kick off by taking Calm before a podcast?

[ANGELA FOSTER] (1:03 - 1:07)
Let's do it. A little cheers. Cheers.

[JESSICA KANE] (1:12 - 1:16)
I always take it before a podcast because... You want to take some PC?

[ANGELA FOSTER] (1:16 - 1:19)
I'd like... Do you know my husband calls this the brain pills?

[JESSICA KANE] (1:19 - 1:21)
My kids call it Brain Medi.

[ANGELA FOSTER] (1:21 - 1:22)
Isn't that funny?

[JESSICA KANE] (1:22 - 1:34)
How many do you take? Two. That's it?

That's it. I took 12 this morning. Did you?

Yeah. It's a pure fad. It won't even break a fast.

But I really think it like turns your brain...

[ANGELA FOSTER] (1:34 - 1:36)
I'm going to take four. Take four.

[JESSICA KANE] (1:36 - 1:59)
I'll take two more. Yesterday morning, I was so brain fogged and jet lagged and I couldn't even wake up. I had a cup of London Nootropic Flow coffee, which has lion's mane and reishi in it.

And then I took like two tablespoons of PC. So it's 24 capsules. And within five minutes, I was like on it.

Like my team was even like, oh, what just happened to you? I was like, yeah, I'm awake now.

[ANGELA FOSTER] (2:00 - 2:03)
How many is four capsules is how many tablespoons? One.

[JESSICA KANE] (2:03 - 2:09)
12 capsules is a tablespoon. So it's a lot easier to take the liquid if you're taking high doses.

[ANGELA FOSTER] (2:09 - 2:11)
Yes. I have taken the liquid actually before.

[JESSICA KANE] (2:12 - 2:25)
And one of my favourite ways is actually just take a little bit of water, pour the liquid into a little water, swirl it around because it's totally hydrophobic and just take a shot of it. Into warm water or... It can be cold.

It can be warm. It can be whatever, room temp.

[ANGELA FOSTER] (2:25 - 3:04)
I wouldn't say hot. I'm going to try high dosing this in future. It's fun.

Just to see. Yeah. Jess, it's so nice to have you here today.

Thank you for having me. You are the co-owner of Body Buyer, third generation business. You've been in the world of cellular energy for a very long time.

I noticed such a difference. I guess let's kick off with, for the woman who is in midlife like me, she's doing, she feels like she's doing everything right. She's training, she's eating well.

She has a high stress load like so many of us do. Don't we all? Don't we all?

And she just can't pick herself up in terms of her energy. What would you say about her cellular health?

[JESSICA KANE] (3:04 - 4:30)
I would say your cellular health is damaged. I would say everyone on the planet's cellular health is damaged. As we age, our cell membrane starts to break down.

And the really interesting thing about it is the cell membrane is the commander in chief. It is the power centre. It is responsible for all the actions of our cell.

And so when I talk about cellular health, I'm actually talking specifically about cell membrane health. Because the membrane is this bubble that protects every single one of our cells. And just like we've become so accustomed to this concept of leaky gut, we get leaky cells.

And when we have a leaky cell, the actions that that cell is supposed to perform stop. And so that is when we see the downstream symptoms of fatigue, of brain fog, of all these issues that high performing women like ourselves experience. And this originates within the cell membrane.

So you can have the right amount of hormones. You can have all these hormones flowing through your blood. The problem is as they land on the cell membrane, and if the cell membrane is damaged, the hormone signalling stops.

And so that's when you start to see those downstream issues, the brain fog, the fatigue, the bloating, the GI issues. All of these things happen in midlife. I mean, really, they start to happen in our 30s.

And it's from kind of 40s onwards that we start to experience them in probably worse cases.

[ANGELA FOSTER] (4:31 - 4:35)
So this is actually happening with men and women? It's just women feeling more with perimenopause?

[JESSICA KANE] (4:36 - 5:50)
I think what the difference with men and women, and I spent some time actually with Dr. Jess Shepherd and Vonda Wright recently, and it was fascinating to hear them speaking about just this extremely sharp decline that women experience, whereas men see this very slow gradual decline of testosterone. And so they're able to test and be smart about supplementation, be smart about HRT if they need it, whereas women, we kind of get this perimenopause and this concept of perimenopause is very new, right? Yes, it exists.

Yes, it's very real. I would suggest that perimenopause is actually a hormone signalling problem that is originating on the membrane. And so it's actually a cellular health problem first and a hormone problem second.

And so as we start to see women's kind of oestrogen decline and then as you know at menopause it just goes off a cliff, what we need to do is really support our cellular health during this decline period. So even before perimenopause in our 30s, in our 40s, as we start to see that oestrogen declining, we are also seeing a severe breakdown in cellular health and that's really the time that you want to focus on cellular health.

[ANGELA FOSTER] (5:50 - 6:03)
That's when you want to dive in. So when we look at the membrane of the cell, what's it doing? It's helping with communication, it's controlling entry in everything out of the cell.

Just give us a really quick kind of snapshot of why it's so important.

[JESSICA KANE] (6:03 - 7:09)
I think for a long time we've thought that like your DNA is the command centre of your body. It's not. The command centre of your body is actually on the cell membrane.

And so the DNA is like an architectural blueprint, it sits within your cells. And in there you've got the nucleus and the mitochondria, obviously which are so important for energy production. Even your mitochondria has a membrane that's really important that can get broken down.

And then there's this fatty layer that's similar to a bubble that you would blow when you were blowing bubbles with your kids when they were little. It's very delicate, it's made up of fats, it's made up of phospholipids, essential fatty acids. In there you also have cholesterol.

Cholesterol is extremely important as we age, so we don't want cholesterol to go too low. And you need these healthy fats to put together this beautiful structure that protects our cell. And what happens with environmental toxins, what happens as we age, what happens with a lack of getting the right nutrients from our foods is we don't have enough of the fat that supplies that cell membrane.

[ANGELA FOSTER] (7:09 - 7:22)
So we just took four body biopsy. I'm taking four at once and a calm. We can go into the calm in a moment.

Where might we find this in our diet? I'm going to go straight for eggs. Is that where we find it?

[JESSICA KANE] (7:22 - 7:23)
100%. Eggs, egg yolks.

[ANGELA FOSTER] (7:24 - 7:25)
Forget the whites. Egg yolks.

[JESSICA KANE] (7:26 - 8:58)
So my grandfather used to literally eat about 6 to 12 eggs a day raw and he would just eat the yolks. He didn't even eat the eggs, the egg whites. So I like to do like a very soft poached egg or I'll put two raw eggs in my morning smoothie.

Eggs are an absolute superfood. If you cannot eat eggs, which I cannot tell you how many women come to me saying, I can't digest eggs. That is your gallbladder.

That is not your body rejecting the egg. You're not sensitive to the egg. It's your gallbladder's inability to process the bile that is needed to digest fats.

So that's liver gallbladder issues. Once you address those, you should be able to eat eggs with no problem. They are an absolute superfood.

After I had my second baby, I could not. I ate some scrambled eggs. I was keeled over in pain, that awful kind of upper right quadrant pain.

And after about four weeks of doing a couple of different things, do you want me to tell you what they were? Body Bio Tadka, which is going to be available in the UK very soon, which I'm very excited about. So that is a bile salt that helps with bile flow.

Gallbladder ND by Premier Research Formulas, which is a fermented gallbladder formula that just helps to loosen the bile. And ox bile, anytime I ate fat. After four weeks of doing those things, my gallbladder was completely fine.

I think I would have headed towards gallstones for sure. And my mother was completely corrected after that. That's amazing.

So if you have gallstones, if you have gallbladder issues, if you have liver issues, that combination works so well.

[ANGELA FOSTER] (8:58 - 9:28)
One of the main things I hear so many women complaining about is bloating. And this is so common in perimenopause. Like I've noticed it myself and it's like, where has that come from?

You know, just phases and you kind of... I feel like I've developed a sensitivity around histamine-containing foods that wasn't there before. But this isn't, you know, I'm definitely not alone.

So many women complain about bloating. What is causing that and how can we address it?

[JESSICA KANE] (9:29 - 11:04)
I think for everyone, it depends, right? There's so many different things that can cause that. But I do know that bloating is...

and histamine in particular is a gut issue, right? We know that. And so when we go a little bit deeper and look at what's happening systemically to women, to men, to people even in their early teens and 20s, now that we're seeing things like colon cancer rise, is we have low levels of a very important short-chain fatty acid called butyrate.

And so throughout life, we have a more disrupted gut microbiome. We have an incorrect amount of the good commensal bacteria in the gut and we're not eating the right prebiotic fibres. And when you have this bad environment of the pre and the pro, those two things need to create the postbiotics and we're not creating enough of those.

And so as we age, I think postbiotic and the main postbiotic is called butyrate. We manufacture it in New Jersey. We're the largest manufacturer in the world.

Many people do not want to manufacture butyrate because it smells. It's produced in the colon. We are not...

it's not naturally sourced. We make it synthetically. But it is not something that should smell good.

This is something that literally comes from the depths of your gut. And it's a critically important molecule, particularly for inflammation. And so most women when they started immediately see better bloating, more regularity.

They're able to digest foods that maybe they weren't before. They feel more clear-headed because of that gut-brain axis. And it's a critically important short-chain fatty acid that people are just not getting enough of in today's world.

[ANGELA FOSTER] (11:04 - 11:08)
And our gut bacteria make butyrate, right? But we can find it also in things like butter.

[JESSICA KANE] (11:09 - 12:05)
You can, yeah. You'd have to eat about two sticks of butter. You'd be eating a lot of saturated fat.

And don't get me wrong, I love butter. I think butter is very good for us. But you don't want that much saturated fat.

And it also... there's a conversion process in the body that if your gut is off to begin with, it's going to be hard for it to convert from butter. So therapeutic doses of butyrate can be anywhere from about two caps to about eight caps a day.

At the higher doses actually when you're taking it after meals, it has incredible benefits for metabolic health and blood sugar regulation, which is fascinating. But it also naturally increases GLP-1, which I've gotten in a lot of trouble for saying. But it is a natural increaser of GLP-1 in the gut, which is very important obviously for regulation of weight and leptin and all of these things that are so important for cravings and, you know, all the things we start to experience that get a little bit out of control in midlife.

[ANGELA FOSTER] (12:05 - 12:30)
Yeah, exactly. This is something that perimenopausal women really struggle with, right, is controlling their blood sugar, having food cravings, abdominal weight gain. So taking butyrate, does that then have an impact on our gut microbiome and help our existing gut bacteria to then produce more butyrate?

So is it kind of like a therapeutic thing that you take for a few months at a time and then you can come off it or how does it work?

[JESSICA KANE] (12:30 - 13:11)
I wouldn't say. To me it's an everyday supplement. This is mainly because of the benefits that I've seen therapeutically with it and the systemic benefits that it has.

So there was an unbelievable study that was actually done in the UK on 10,000 people with Lynch syndrome, which is a propensity towards a certain type of cancer and they ate a green banana every single day and they monitored these people and they had a 60% reduction in total body cancers. Not just GI cancers, total body cancers. And why is that?

It's because a green banana, which I don't know if you've ever had one, but it's a little hard to eat every day. It's a great thing to put in a smoothie, but it's a little difficult to eat a full green banana with that kind of...

[ANGELA FOSTER] (13:11 - 13:11)
Yeah, it's tough.

[JESSICA KANE] (13:12 - 14:18)
It gets like stuck in your mouth. I tried it. But the reason is green bananas are resistant starch and resistant starch is the prebiotic fibre that creates butyrate in the gut.

So the issue is we're not eating the right types of fibre. So eating a green banana a day, eating cooked and cooled rice or mashed potatoes... Freezing sourdough is what I do.

Yeah, freezing sourdough, exactly. All of these things are prebiotic fibres that when you have the right commensal bacteria, create butyrate. But it's just becoming too hard.

And then you add on pesticides, glyphosate, antibiotics, all of these chemicals that have been introduced over the last 100 years. All of these are disrupting our gut microbiome. And so I don't see butyrate as a therapeutic thing that you use short term.

You can try it. I find that typically when people go off of it, then that bloating comes back. So when they're starting it, they find all the benefits and it's something that you'll see within a couple of days.

It's really incredible. But I think in today's world, we just need these nutrients that we're not getting enough of from our foods.

[ANGELA FOSTER] (14:18 - 14:29)
Because we have so much coming at us, right? That's the thing that we didn't have before. So if we're taking butyrate then, you mentioned take it after food.

Is that going to be after every meal or just on your largest containing meal? What's the best way to take it?

[JESSICA KANE] (14:29 - 14:54)
It really depends on the person. Trial and error, see what works for you. It depends on your weight, depends on if you're looking for kind of weight loss objectives as well.

I like to take it after a meal because it helps with the metabolic benefits. I will wear a CGM and actually see that if I eat something, let's say I indulge in dessert or let's say I'm enjoying a meal out in a restaurant, eating things that I normally would not, I will see that my blood sugar is actually more regulated when taking butyrate.

[ANGELA FOSTER] (14:54 - 14:57)
That's super interesting. So it's almost like having berberine or something like that.

[JESSICA KANE] (14:57 - 15:12)
It's a little bit like a berberine. It's almost a little bit more like a GLP-1 than a metformin because berberine is very similar to the drug metformin in its metabolic benefits. It's a little bit more similar almost to, and I can't say the prescription terms, but we know what they are.

Semaclutide.

[ANGELA FOSTER] (15:12 - 15:58)
So then it helps with cravings and things like that. If you're getting value from this show, the single best thing you can do to help us keep bringing you the highest calibre guests is to subscribe or follow wherever you listen or watch. It takes 10 seconds, but it genuinely makes a difference to the quality of the guests we bring you week after week.

Yeah, amazing. Going back then to the phosphatidylcholine, we were talking at the beginning. So my husband calls them brain pills.

I love it. I've tried the liquid as well. How is that affecting our brain?

Why do we feel more switched on? I know when I look at the articles on your website, for example, I think it says allow like 8 to 12 weeks for it to start to work. Actually with that, I noticed it very quickly.

I love that.

[JESSICA KANE] (15:58 - 17:39)
That's probably because you're pretty clued into your health and you're very intuitive and you can sense things. It really depends on your state of health, right? If you are somebody who is extremely high performing, you're tuned in, you're working out all the time, you've got your right supplement routine, you may start PC and you may feel immediate brain clarity, better memory, better recall.

You're going to notice the brain benefits first more than anything. But remember the 32 trillion cells in a woman's body are not just in our brain. They are all over.

There are liver, there are gut, there are skin. You actually notice better skin quality and laxity because these fats make up the cells that make up our skin. And so you'll see it systemically, but then there's the other population of people who may be experiencing something more acute and may be dealing with mould toxicity, may be dealing with an autoimmune condition and they may have to start PC at a little slower and lower dose.

So I always recommend start with one cap, see how you feel, half a teaspoon, see how you feel and then build up from there. Because for those people, the terrain is not ready to accept something that is so... It actually has a zeta potential to it.

It has an electrical charge to the supplement and we've tested it. It's fascinating. And so when that's introduced to a body that is not in a great terrain, it can almost overwhelm it.

And so sometimes you will experience Herxheimer headaches when you started, things like that. But that is definitely on the rare side. Those are people, you know, I'm somebody who's dealt with mould, Lyme disease, so many different things.

So I sympathise with the chronic illness community. So I just want to point that out.

[ANGELA FOSTER] (17:39 - 18:01)
It's really interesting what you're saying there, kind of around the electrical signature of it. So if someone's got issues like mould, like Lyme, it just kind of turns up the volume. So you go slowly with it, that would be the thing.

But it just then makes me jump straight to if this is kind of increasing our energy, our frequency, our vibration, what impact is it having then on things like HRV?

[JESSICA KANE] (18:01 - 20:34)
It's fascinating. So, you know, HRV I think is such an interesting thing to monitor. And I think when you think about body biosupplements, we are a company that is so focused on cellular health and the cells are the foundation of everything in our body.

So when your cells are not functioning properly, your mitochondria are not producing the right amount of energy, your sleep quality is not that great. Your ability to handle stress is lower because the neurotransmitters, the serotonin, the dopamine are not able to land on that membrane and perform the actions that they need to. Remember, all those things happen on the cell membrane.

And so it's this foundational layer that affects every other system in the body. And so what I have seen countless times, which I find really fascinating, is when people start on body bioproducts, let's say you start on what I call like the beginner protocol. So it's a quadruple products of...

I call it cell essentials. It's PC, balance oil, butyrate and remineralise. When you start on those products, you're giving your body this really great foundation to build everything off of.

And within a few days, you will actually see that your HRV goes up because you are able to handle more. Your central nervous system is literally firing and it's working and it's getting you in between the sympathetic and parasympathetic state as it should. One of my favourite little hacks for HRV is actually using body biocalm.

And so I had a group of people in our wellness community who decided to run... they were all wearing an Oura ring and they all started taking body biocalm. And I'm telling you, their HRV went from like the 40s and 50s to the 90s.

So they were just taking two capsules before bed. That was it. And it went from all the way from, you know, in the tank to the 90s.

Yeah. So I take two caps before bed every single night. If I wake up in the middle of the night, I take it.

If I wake up in the morning and, you know, I'm looking at 700 emails and, you know, 60 Slack messages and so overwhelmed, I take two. And I feel it just my flow state is PC and calm together because I feel like those two things just activate your brain and allow you to like get on and just lift the weight that's on your shoulders of, oh my God, oh my God, you know, there's so many things happening and you can just calm and approach each one methodically.

[ANGELA FOSTER] (20:34 - 20:54)
Well, this is such a common thing, right? Especially for the midlife woman. You're just like so many open tabs in my brain.

It feels like you've got all these tabs open on your computer and you're trying to handle everything. So for someone who's looking at, I really need to get some kind of deep focus work done. Then the body by a PC in combination with calm would be the way to...

That is my hack.

[JESSICA KANE] (20:54 - 21:31)
I mean, I've had people write to me, men and women, and say like, you need to start talking about this as what gets you into a true flow state. Because I mean, I'm sure you've experienced it. There's just a different level of productivity that you can get into when you've got that time to focus and you need to just dedicate time to getting these things done or whether it's in meetings, whether it's in presentations, whatever it is, you vibe differently when you are in that state and you can tell that your brain is powered.

And we need these things to power our brain in today's world. We're just not getting enough of it from our foods and from the environment that we live in. It just affects us too much these days.

[ANGELA FOSTER] (21:31 - 22:23)
And what I've found is like when you optimise in that way, it gives you back time. I think the thing I'm so interested in that the body by our products help with and have helped me is you can think about health from multiple angles. So if we look at lifespan, we're really good at extending lifespan, but we just don't necessarily extend it in the absence of disease.

So then I think everyone got really focused on health span and it's like, okay, how do I stay healthy? How do I not have chronic disease? But there's another level, right?

Is that once you have all of that dialled in, you can start looking at peak span. It's like, how long can I be at my best? And I think that's what I've noticed is it just helps move things up a notch level so that you can not just kind of cope with everything.

You're not just kind of surviving again. Yes, I can handle it. I can handle the kids.

I can handle the job. I handle my team, handle all these things. But actually, you've got more capacity.

You're thriving instead of surviving.

[JESSICA KANE] (22:24 - 24:10)
I'm one of them, right? I'm a testament to it. And there's times that I break down.

There's times that I do too much and I notice I have to back it up. I mean, we have a third generation family business that my husband and I run together. So that's a whole drama in itself, which we do very successfully.

I'm very proud of us. He's the architect, the builder, and the person that makes everything happen, right? We have 90 employees manufacturing the products.

We have this vision that's been passed down from my grandfather who started the company in the 90s. We have tens of thousands of doctors all over the world who trust our products and use our products and trust them because they are effective. We have that.

It's not a burden, but it is something that you carry with you that is very important to maintain that integrity. And then we're raising three small children. We have kids who are four, six, and eight years old.

You want to be present. You need to be around with them. I'm travelling a tonne as, you know, the face of the brand, trying to translate this complex science into things that people understand.

And there's definitely been times that I burned out. And I know, okay, this is coming on. I can sense it.

I need to slow down, prioritise the basics, prioritise sleep, prioritise taking the right supplements, prioritise nutrition, prioritise circadian biology and getting outside in nature, getting vitamin D when and if I can. Going back to the basics, I think it's so important for women like us. I actually often say that, like, I don't like the whole lean in movement, the whole we can do it all.

I don't think that we should put that pressure on ourselves. I think that you should optimise yourself for peak performance. And in there, you can feel better doing all these things and we can achieve them in a great state.

We shouldn't struggle to get there.

[ANGELA FOSTER] (24:10 - 24:43)
I so agree. I think it would be really helpful, Jess, actually, just thinking, listening to you as you're saying this is if you could walk us through two things, I think this would be really fun for listeners. So the first one would be a normal, if there is such a thing as a normal day with three kids and a big global business, but you're clearly a high performer and you're optimising your health at the same time and having time with your kids.

So on a normal day when you're not travelling, and then we'll look at travel separately, what does it look like for you? Because you can't always guarantee an amazing night's sleep with three kids.

[JESSICA KANE] (24:43 - 30:12)
No, you cannot. My kids are homosick right now, actually. I'll take a screenshot and you can share it with your listeners in my calendar.

I time block my calendar very specifically, very intentionally to have the time in the morning. So I'll start with my morning routine. I wake up around typically 5.30 in the morning. If I can go get in my sauna space light, because that's combining both red light and sauna. I will do that partnered with some red light on my thyroid because my thyroid is my kind of weak point. I tend towards like autoimmune Hashimoto's and I don't want to go there.

So doing everything I can to not go that way. Quiet, I need that peace in the morning before the chaos starts. And so then I will do, while I'm in the sauna, I do a large glass of water with minerals and electrolytes.

When I get out of the sauna, I do a shot of PC. So I'll start my day with that fat because I want to be somebody who can eat breakfast that early in the morning, but I just can't. It's like, I can't do it.

I'm trying to get the breakfast as early as possible. But I also don't want to like go clamouring through my kitchen, waking my kids up. I think that that peace and quiet for me is more important than cooking myself breakfast.

So I'll get like a little bit of those nutrients in with the fat. And then my brain starts powering. I have my coffee, mould-free coffee with raw milk, whole milk.

And then I will get on with, you know, doing everything for the kids. So I'm making lunches, I'm making breakfast, very protein-heavy breakfast for the kids. So maybe like half of a grass-fed, grass-finished burger, eggs, some sourdough.

Occasionally, if they want cereal, we have an amazing cereal in the States called Lovebird that I absolutely love. It's great fibre for them. I create a morning smoothie for them every single day that is a chocolate protein powder, raw milk, remineralised body biobalance oil.

And then they get that. And if they're sick, they might get some little tinctures. If they're, you know, dealing with something, they might get something specific.

So I keep it pretty simple for them. When I get back from drop-off at 8 a.m., my husband usually makes me breakfast. Protein-heavy, I'll usually have some sardines, some sauerkraut, that burger, poached eggs, lightly poached, coconut cult scoop with a little bit of seeds.

I do seed cycling. So if it's flax and pumpkin or sunflower, depending on my cycle. And then I'm like, and then I take my supplements, my B vitamins, my liver support.

Maybe I'll take some more PC, some butyrate. And then, you know, my day is off. Right now at this phase in my life, I wish I could work out more.

I'm trying to prioritise. So what I've done is I just got myself a bunch of kettlebells and I keep them in my office because then in between meetings and things, I can do my squats. I can do like a simple 20-minute kettlebell routine.

If I can get to a class, it's great. I like to alternate Pilates and kettlebell workouts. So I'm really trying to get my weightlifting up.

I think that's really, really important. And heavyweights and like, don't mess around, hire a trainer to give you the right posture and then go from there or get into like a kettlebell class where you really know you can figure out the right technique. I think that that's really important.

At my office, I have another sauna space light, a single light that I turn on. I crack a window to make sure I'm getting natural sunlight in. I go for as many walks as I can in between.

I love to have lunch with my marketing team as much as possible. So we will make lunch together. We've got a nice little kitchen in our office and have that time to just connect and chat about things and have those in-person meetings, which I think is great.

Try to end my days, depends on if the kids need me or I'm taking a dog to the vet or whatever things are that's happening around. I've got a wonderful team. So I have my mom close by as well as a full-time nanny.

You cannot do all this on your own that help get the kids to sports and things after school. And then I try to be home. God bless her.

My mother is my saviour and makes us dinner almost every night. I love to cook. Cooking is my love language.

I wish I could do it more. And I'm so happy that I have her close by to help me with that. It's changed.

It's changed from that being a stress to being so relieved that I get to come home and really enjoy dinner with my family. And we get to spend that time. At that point, phones are away always.

You walk in the door, phones are away for my husband and I because you can get very easily drug into a kind of 18-hour workday and you need to be present and you need to have that time to connect with family. So until they are in bed, there's no phones. And then even once they're in bed, I really try not to go on my phone.

I try to read at night. I'm always dimming the lights in the house at night. Circadian biology, really trying to get those natural, the natural melatonin released as opposed to taking a supplemental melatonin.

Although I don't think it's bad if you have to. Although I don't think you can get it here, can you? You can't get it here.

And then sleep is really important to me. I try to go to bed latest by 9.30. Nine is my sweet spot. And that allows me to get my eight hours is really my go-to place.

Very dark room, red light bulbs in next door bed. Looks like a red light district. Sexy, why not?

But it really helps with, you know, if I'm just reading before bed, it helps me to regulate. And I just feel so much calmer with those red lights.

[ANGELA FOSTER] (30:12 - 30:34)
I think it makes a big difference. I think it does too. I have it in my lamp.

And then also those little lights that go on the bathroom tiles, you know, like magnetic and they sense. So it's a red light. It's just like you charge it up.

And then when you walk in the bathroom, it just comes on. So if you wake up to use it, it's not jarring. Is there anything that you take as part of your supplement routine at night before you go to bed?

[JESSICA KANE] (30:34 - 31:39)
Yeah. So I take glutathione at night, two liposomal glutathione that we make. It's truly liposomal.

A lot of liposomal supplements on the market are just using lecithin. They're not actually liposomal. So it's very important with glutathione because glutathione cannot be absorbed well in the body.

And so if you're going to take a glutathione supplement, it needs to be properly liposomal, not just... I think there's... If you want to take a sachet, there's a great company in the UK called Ultrian in the US.

It's called Live On Labs. And they make a good supplement as well as ours. And so I'll take that at night.

Occasionally, a couple nights a week, I take Tadka. And every night before bed is Body Biocalm. So that is my like non-negotiable right before bed.

I've been also taking recently magnesium glycinate, which I really like. And I find that helps keep me regular, which obviously is going to help with bloating. So the combination of butyrate and mag-glycinate, like even when I'm travelling, is really helping keep the bloating away even though you're eating stuff and you're on aeroplanes and travelling.

I'm finding that combo really works well.

[ANGELA FOSTER] (31:40 - 31:45)
Really working. So you said you take the Tadka a couple of times a week. Yeah.

Tell us about that. How's that?

[JESSICA KANE] (31:46 - 32:45)
It depends on the person. If you're somebody who has like non-alcoholic fatty liver disease or if you're somebody who has liver issues, elevated liver enzymes, you might need that longer term. If you are somebody who has a history, a genetic history of Alzheimer's, Parkinson's, you may want to be taking Tadka every day because it has neuro benefits.

For me, I find that it works best when I just take it a couple times a week because I don't find that I need it. I'm quite intuitive with supplements. I don't find that I need it all the time.

So if I'm starting to feel that like fat, I eat a lot of fat. If I'm starting to feel that taxing on my liver gallbladder and I need some bile support, bile is this substance that like thins out the fat and allows the body to actually absorb it. And so it's going when your bile is flowing, when your bile is thin and when your bile is functioning, you're not going to get gallstones because that's the sludge that gets built up in our gallbladder that will eventually cause gallstones.

[ANGELA FOSTER] (32:45 - 32:48)
So I just take it every few days. Before bed, not with food?

[JESSICA KANE] (32:48 - 33:03)
You could do either. Okay. Yeah, you could do either.

There's, you know, I think that's a really interesting topic actually in health and wellness because some people get so dogmatic on this is when you have to take it and this is how you take it. I find that you just have to experiment for yourself and see what works.

[ANGELA FOSTER] (33:04 - 33:17)
You know, I think in general... People might get any kind of sensitivities or irritation if they're taking it on an empty stomach or a little bit like you're saying with the PC, if they're going through any issues that they're dealing with, do they need to go like slow with it?

[JESSICA KANE] (33:17 - 34:00)
I don't find Tadka to have that effect. Take one capsule instead of two. If you are concerned at all, butyrate can because butyrate has a low pH and so you want to be careful with butyrate.

You always want to eat it after a meal because some people can say like if they eat it on an empty stomach, they can get acid reflux. I don't, but it depends on each individual. Remember, anytime you're taking something on an empty stomach, if it's a vitamin, your stomach doesn't know the difference between that or a large salad with protein.

And so it's still going to secrete all of the digestive enzymes and the digestive juices and the HCL to break down that food. And so it might overcompensate and create too much and then you experience acid reflux.

[ANGELA FOSTER] (34:00 - 34:33)
Yeah, so that's something to kind of be careful of. One thing I really want to kind of track back on, when you were talking about the PC, you were talking about how it even affects skin health and how the fats are really good for you and then you mentioned the balance oil, which I think is just amazing for like skin and hair. And then there's also the omega-3.

So I think for someone thinking about this, because I love omega-3 as well, how do these fit together? I know your omega-3 is actually very different than most. It would be really helpful just I think for viewers and listeners to understand that trio.

[JESSICA KANE] (34:33 - 38:05)
So if we separate out the two different types of fat, healthy fats, you have phospholipids and you have essential fatty acids. I actually even heard Huberman talking about this the other day. The two most important nutrients for our brain are phospholipids and essential fatty acids.

We'll put aside phospholipids for a moment because these are two different classes of fats and focus on the essential fatty acids. If you Google the essential fatty acid pathway, you will see back from, you know, biology and probably college, because not many people did this in primary school or in high school, the two mother essential fatty acids are linoleic acid and alpha-linolenic acid. And downstream from that are all these biochemical processes and pathways that work because of these two.

Downstream from the omega-3, alpha-linolenic is EPA and DHA. Now, the conversion from ALA to EPA, DHA is low. We don't often convert that.

The main sources of linoleic and alpha-linolenic are seeds. And remember, these are essential fatty acids and the reason they're called essential is because our body doesn't make them. So, we need to get them from our outside diet.

So, seeds are the place where you're getting most of these and when we start thinking of seed oils and we start thinking of all these oxidised things, we start to avoid them. But I'm here to tell you that these things are very good for you when they're in a whole food raw form. So, walnuts and pumpkin seeds and sunflower seeds and flax, these things are great in moderation because they are supplying this essential fatty acid pathway.

Where we get confused is we think we can take a bunch of fish oil, omega-3 down here, and it's going to do everything that this whole chart entails. But what's interesting is the omega-3s don't cross over to the omega-6s. So, some people have been taking too much omega-3 and their ratio of 6 to 3 is actually way off balance.

What's interesting is if you do a blood test to look at your omega-3, omega-6, it's looking at the circulating plasma levels of those two things. That will be greatly affected by what you have eaten in the last few days. It's not looking at what's happening to your cells.

In order to figure out how these oils are affecting our cells, you need to do a red blood cell fatty acid analysis and those are complicated to get. I've seen thousands of them. So, I know that when you take too much fish oil, it offsets the levels of the other.

So, what's in balance oil are there's two parent essential fatty acids, the linoleic and the alpha-linoleic, and then the resolvin, which is fish oil, it's cold-pressed caviar. So, it's a phospholipid form of fish oil, which is the best form you could possibly get, is our fish oil. So, it's totally confusing.

It's completely overwhelming. You hear that omega-6 is bad. Not all omega-6s are bad.

They're actually really important for our mitochondria. They're really important for ATP production and it's incredibly important for skin laxity and bounce. I often say that balance oil is the product that makes your cells bouncy like a grape instead of shrivelled up like a raisin.

And so, so many of us have been avoiding fat for so many years because of the 1980s and the 1990s and everything low-fat and processed. And now that we're getting back to a place of whole food forms of these things, I think it's really important that we start talking about there's some good omega-6s out there that are really important. So, the balance oil has both, right?

[ANGELA FOSTER] (38:05 - 38:16)
And then further downstream, would you take that just a few times a week then? It's not on every day. A lot of people are high-dosing fish oil every single day.

Exactly.

[JESSICA KANE] (38:16 - 38:31)
When you high-dose it, you're omitting the others and you're avoiding an entire... I would love to do a study where you look at people who just take fish oil and people who take balance oil and just look at their skin quality. It would be really interesting to do, although these things are impossible to organise.

[ANGELA FOSTER] (38:31 - 38:51)
Yeah, I remember when I was having a conversation with Dr. Bill Harris, he was talking about how he has obviously done like 30 years of research on omega-3, but he was saying just how important omega-6s are, but they've been given a lot of bad press, right? Unnecessarily so when we need them. So, the resolvent, the fish oil, would be taken like three times a week, would it be?

[JESSICA KANE] (38:51 - 39:12)
Yeah, I take it every other day pretty much. And in the summer, you know, I think it's also really important to get fresh fish when you can. So, if you can eat well, you know, during certain seasons, you're going to have more fish in the summer, in the spring, in the kind of warm weather time.

So, if you can get whole food fish forms, you're actually going to get a lot of the good omega-3s as well.

[ANGELA FOSTER] (39:12 - 39:36)
A lot of people worry about, when you talk about fish, right, about microplastics. Now, this is something I heard you talking about on another podcast, which just kind of really blew my mind, is you were talking about an individual who'd done Brian Johnson's microplastic test, and then they were high dosing the Body Bio PC. Two tablespoons a day.

Two tablespoons a day, and I think, was it within three months? Was it that short?

[JESSICA KANE] (39:37 - 39:38)
It was within one month.

[ANGELA FOSTER] (39:38 - 39:43)
Within one month, the microplastic count went to zero on the test. This is incredible.

[JESSICA KANE] (39:44 - 41:28)
The macroplastics, so there's micro, nano, there's all these different categorisations. The largest molecule went, just dropped. Straight up.

The nanoplastics take longer to get out. And there is an argument that it's hard to detect nanoplastics in a fingerprint blood test. But the other option is biopsying things.

And we're not going to go biopsying people's brains to see how much nanoplastics there are. Although, I think they're doing that, but that's not something that you can readily test. That would be very expensive and kind of crazy.

So, yeah, he did the fingerprint test. It was fascinating. And basically, kept with...

So, really started to just eliminate, you know, not drinking out of plastic. That was something that he was doing anyway. So, it's not like he had a tonne of lifestyle changes.

And what was interesting is after... So, he did it over six months. After month four, you were seeing the microplastics go down significantly.

The nanoplastics go down significantly in the different particle sizes. I can send you the link to his website, so your listeners can actually take a look at his experiment. This was completely outside of body biocitizen scientists that did this.

He started drinking water from his gym and he started drinking out of a plastic bottle and they started to creep up again. And so, it's really important that you partner both the avoidance of these things, but also taking the right fats, because what fats do is they go into the body and they grab on to fat-soluble toxins and they excrete them from the body. When you just sit in a sauna, you're not just sweating out the fat.

Sorry, you're not just sweating out the microplastics. You need the fat to actually grab on and excrete it through our sweat, through bowel movements and through urine.

[ANGELA FOSTER] (41:28 - 41:36)
So, would you take the PC in combination with a sauna session? Like before or after, what would be the most optimal time?

[JESSICA KANE] (41:36 - 41:50)
PC is your everyday supplement. So, I usually take it in the morning. Your sauna, my two supplements I take when I go into the sauna are liposomal glutathione and Tadka.

So, you're getting the liver health and then you're getting the antioxidant support to help remove the fats.

[ANGELA FOSTER] (41:50 - 42:04)
And what's the kind of maintenance dose of the PC for somebody who just wants like really good cellular health versus someone who is maybe thinking I'm going to go on a bit of a detox, like try and flush out some of these plastics in the body?

[JESSICA KANE] (42:05 - 43:00)
Yeah, you could take, you know, the dose on the bottle is two capsules a day, which is half a teaspoon. If you wanted to increase that, you could take as a maintenance dose, you know, a teaspoon a day, five capsules. If you want to mega dose it, there's no high dose of...

This is an essential nutrient. It's not a supplement, it's not a vitamin. It is something that is in our body every single second, every millisecond we are making it.

And so, if you want to mega dose it, you could go up to... I mean, I've seen people go up to six tablespoons a day for people who are dealing with neurodivergent children or neurodevelopmental diseases, neurodegenerative diseases. So, the highest I've ever gone is three tablespoons a day.

And that was at the height of mould toxicity, really trying to flood my body with the right phospholipids because it's amazing how much mould just disrupts the cell membrane, Lyme disease disrupts the cell membrane, all of these things, COVID completely disrupts the cell membrane.

[ANGELA FOSTER] (43:01 - 43:44)
So, by having a good cell membrane, you're then actually then also protecting yourself against a lot of... Yeah, exactly. Are there any downsides?

You've mentioned like if someone's sensitive, they might need to build up gradually, but if you were taking quite a big dose, could that then reduce what your body's making? No, it doesn't work that way. It just floods this pool, the pool that it can then come from for the body.

It's very interesting what you shared around autism, right? There's lots of people with neurodivergent kids. Yeah.

What benefits do you see with that? I mean, I've heard you speak of people who are completely nonverbal actually getting some of that, not necessarily full sentences. But what's the effect on the brain?

Is this all linked to neuroinflammation? What's going on there and how is it helping?

[JESSICA KANE] (43:44 - 45:47)
It has a big tie to neuroinflammation. Typically, you'll see in children with autism, they have high levels of toxicity as well. They're born with those high levels.

I think we're just really on the precipice. There's a wonderful researcher in America doing incredible research on mitochondrial health and how, you know, we often say like, oh, well, my grandparents smoked two packs of cigarettes a day and they lived till 95. Well, they weren't burdened by the world that we live in and the world that our parents were living in and what we were handed down.

And I think each generation is unfortunately getting sicker and there's no denying that. You know, 100 years ago, I don't think you were seeing kids at 20 years old with colon cancer. It just wasn't happening.

And so what we're seeing is each generation has a higher toxic burden that is passed down through the maternal mitochondrial DNA, which is a pressure on women, like what an unnecessary pressure we have. But we are... this is what happens.

We hand down this mitochondrial DNA and I feel so passionately about helping moms understand that they can clean up, they can do a protocol before conception that will really help to reinforce and clean their cells and their mitochondria. I'll give you that whole protocol if you want to link it as well. So what we're seeing is they're born with this higher toxic burden, they're studying it, they're doing amazing research.

You're seeing very low levels of butyrate in the gut. You're seeing very disrupted cell membrane health and high levels of neuroinflammation. And so we often talk about it when I've spoken with doctors on this subject who work directly with children with autism about this brain on fire concept.

And the PC is going in and supplying a lot of the raw nutrients that these cells need to help deal with that inflammation. So by no means am I saying that this is a cure. There is no cure.

But this is a tool that can absolutely be useful for parents to use to help their children with the nutrients that they need when they're definitely not getting enough of it from their diet.

[ANGELA FOSTER] (45:47 - 46:08)
So helpful. When we're thinking then about a common thing would be like just poor mood, anxiety. These are also really common symptoms in midlife.

Is there anything that you can share here that would help? I know we've talked about calm, but what are the key things that can improve the way that we actually feel?

[JESSICA KANE] (46:08 - 47:40)
Yeah, I mean, it's so interesting to go into your GP and do your blood tests and they look at it and they say you're normal and you're sitting there thinking, I feel terrible. Why do I feel so tired? Why am I so brain fog?

Why am I so bloated? I think that we need to reframe this whole midlife section. I think we need to reframe health in general and understand that it's not just a hormonal issue.

It's also a signalling issue. So if you think about hormones as the key and the cell membrane is the lock, the key is there, but if the lock is broken, the key is not going to work in the lock. And so we need to look at the foundation of our health at the cellular level and build this resilience from there.

And I cannot tell... I mean, I have countless, countless thousands of people who have come to me saying this has changed my life. It's amazing how different I feel when you just get the right essential nutrients in.

And unfortunately, I wish I could say you can get enough by eating steak and eggs and, you know, fibrous vegetables. It's just hard. It's hard to mitigate it all.

And so instead of reaching for a peptide, instead of reaching for NAD, which I think is great, it's not going to do what it's supposed to do if the cell membrane is damaged. And so I sound like a total broken record because I'm talking about something so geeky as the cell membrane, but I really do think it's the key to unlocking how you can feel better in midlife.

[ANGELA FOSTER] (47:40 - 48:30)
Well, I think it's really important because there's, you know, I guess there's sort of three groups of women almost when we look at hormone therapy, menopause hormone therapy, is there's some women who, you know, they felt like they fell off, they start taking it, they feel pretty good and they're doing all the other things that we're talking about. And so it kind of just elevates their overall state. So now they feel back to being them and that's great.

But then there are two other groups of women that I see. One who basically they start hormone therapy and they're like, yes, I feel amazing. This is so good, it's having an impact.

And then it starts to peter off and they kind of need to adjust the dose or they're like, it's just not working. So I was, yeah, I want to go into it with you because there's that woman, right? And then there's the other one who's like, I took menopause hormone therapy and I felt terrible.

So I'm not going anywhere near it. Can you clarify what's going on for both of those women?

[JESSICA KANE] (48:30 - 49:21)
I think they have what they're having. Their problem is that the signals are not working, right? The signals that are reaching the cells are not actually working.

And so if this cell membrane is the control centre of our cells, in order for the hormone to work, it has to land somewhere that can actually transmit the signal. And that piece is broken. So you can throw more hormones at it.

But if the cell is not actually absorbing it and utilising it, what's the HRT actually doing? And so you need to have this foundation, I think, particularly before HRV. And I think HRV is life-changing.

I also think for those women who are like hyperreactive and may have negative, oftentimes it also has to do with like how much, what they've started, is it the right amount, is it the bioidentical? That piece also comes into play there.

[ANGELA FOSTER] (49:22 - 49:32)
Yeah, but as you say, the health of the cell and the mitochondria is so important. Mitochondria, really important because oestrogen affects mitochondria. Oestrogen affects the entire cell membrane.

It's interesting.

[JESSICA KANE] (49:33 - 50:26)
As you age and have less oestrogen, it's almost like a protector of the cell membrane in a way too. So it's so important. There's an incredible enzyme called PEMT that converts phosphatidylcholine from food in the body into utilisation in the cell.

So it takes that PC from food and it goes through this process and it gives you the right PC for your cell, for your cell membrane. And it's this beautiful little, it's a bilayer. So it's these little molecules that come together and lock in to protect the cell.

PEMT decreases when oestrogen decreases. So it's like we're almost like screwed, right? And you really have to be more vigilant.

The men, unfortunately, because of this. So I think the more we know, the more we are empowered to understand these things, the more we know about the benefits of weightlifting, of creatine, of taking care of your cells, of HRT, the better we are going to feel as we age.

[ANGELA FOSTER] (50:26 - 50:50)
Yeah, when you put all those things together with the right supplement protocol, it works super well. I'm interested because you just flew in from New York yesterday and clearly you're on top form. So I'd love to know your travel protocol because I think when we think about going on a plane, right, we're just building up this massive positive charge.

What have you done to land here with such high energy?

[JESSICA KANE] (50:50 - 53:05)
I think I've been on 10 planes in the last two weeks. It's really crazy and my voice is taking a toll. I'm a little more hoarse than I would normally like to be.

A couple of things that I do, I carry a big bag, it's about this big and I have all my supplements in it. I put them into little Ziploc baggies. I'm not afraid of microplastics from my Ziploc bags leaching into my capsules.

I put them in Ziploc bags, I label each of them. I've got my glycine, my vitamin B, I've got my PC, I've got balance oil capsules, I have EPO capsules, evening primrose is really important in your luteal phase or your follicular phase. I have all of these things.

I have H2 tabs that I use on the aeroplane. So I try to drink as much hydrogen infused water as possible on the aeroplane and when I get off, creatine is really awesome for jet lag. There's some great studies there.

And I just optimise that and I optimise food. So I bring a tonne of snacks with me so that I'm not eating plain food. Plain food tends to be really, really high in sodium.

Sometimes like they, you know, I had a salad on the way over and that was fine. I'll try and pack my own food if I can. When I'm with my kids, I'm packing, you know, 65,000 snacks and alternatives to terrible treats in the airport.

But I also am an aeroplane, all things go so that they are quiet. So I use everything I can. But I will even like on the way out, I made like little gluten-free biscuits and I had some meat sticks and I had olives and I'll pack, you know, specific snacks that I like.

So I've got enough food. When I arrive, I really try to optimise my sleep. So I'll bring a sound machine, a portable sound machine.

I've got my mouth tape. I make sure the room is very dark. My husband thinks I'm absolutely nuts because I'll go around putting stickers on televisions where there's little...

I'll turn the clock off. I, you know, I need pitch black darkness. And when I do travel, I use melatonin.

If I'm doing a time change, I will use melatonin so that I can help to kind of set my circadian rhythm a little quicker. And I find that really helps. It's working.

It's working. I mean, I got eight hours of sleep last night, shockingly.

[ANGELA FOSTER] (53:06 - 53:09)
That's amazing. Yeah. It's amazing.

And it's a beautiful morning here in London.

[JESSICA KANE] (53:09 - 53:13)
It really is. Yeah. So getting that sunlight first thing in the morning really felt luxurious.

[ANGELA FOSTER] (53:13 - 53:21)
When I came over the river this morning, I was just like, oh, London is just such a beautiful city. Yeah. When the sun is shining, it's kind of hard to be, isn't it?

[JESSICA KANE] (53:21 - 53:22)
It's so true.

[ANGELA FOSTER] (53:22 - 53:53)
One last place I think we haven't been. And I wonder just how it might help is so many people are dealing with trauma at the moment. And the thing with trauma is you think about going for psychological therapy because you think it's in your head.

It's actually in your body as well, right? Your cells are holding onto it. I'm curious, everything we've been talking about, it leads me down the path.

Can the things that you're speaking about help optimise the health of our cells, that it might even help us start to let go of some of the trauma?

[JESSICA KANE] (53:53 - 55:51)
Oh, that's a deep one. I am somebody who's had a lot of trauma in my life. My father died very traumatically when I was 18 years old.

He committed suicide. And so I am very familiar with the concept. Trauma has such an incredible, incredible role in our health.

And my GI system was never the same. That moment, all my GI problems started. And throughout my 20s, I mean, I was in and out of gastroenterologist, doing colonoscopies, doing endoscopies.

You have IBD, you have this. I think I would have headed towards a place where I would have eventually had Crohn's or colitis or one of those things had I not really taken care of my health. I think that it's not a cure.

I think it's part of the puzzle. I think cellular resilience is really important. I think the mental peace and taking care of your mental health is extremely important because our traumas are also combined traumas of our ancestors.

And these things are passed down in ourselves that we are given from our parents. And I find that so fascinating. Dr. Mark Wolin is a wonderful author who wrote a book called It Didn't Start With You. That book changed my life. And it's incredible. And I've also started doing something that I think is really important in combination with how well you know I take care of myself.

I also do something called internal family systems therapy, which I love. And that has really helped get me to a place of understanding the different parts of ourselves that are developed from trauma. And I think it's changed who I am, to be honest with you.

It's fascinating. But I don't think there's any easy way out of trauma other than addressing it and dealing with it, not throwing it under the rug. Making sure it's something that doesn't become who you are, but something that is a part of you that you recognise and work with.

[ANGELA FOSTER] (55:52 - 56:15)
I totally agree. And recognising it's a whole mind-body experience, right? And the mind's informing the body and the cells.

And then that information's coming back and re-informing how you feel. One last place to go, I think, is energy. B vitamins.

They're so important. And they work synergistically together. I think that's an important piece for people to understand.

Please can you explain more about that?

[JESSICA KANE] (56:16 - 57:34)
I hate when people tell me that I take a B12. I'm like, no, take a B complex. You have to take the full spectrum complex.

When you just take one, it offsets levels of others. And so, yes, you might be low in a B12 and maybe you want to supplement that for a month. But I really suggest that women, in particular, and men, it's actually very important for men too, take a full spectrum B complex.

And so that is something really important. It's also really important to understand whether you can metabolise, whether you can actually utilise folate or not. If you have the MTHFR genetic mutation, make sure you are not using a B vitamin that has folate in it.

You want one that has 5-MTHF or methylfolate is really important so that you can actually utilise the folate in that B vitamin. But I mean, I took one this morning. I take it every single day.

If my HRV is low, if I'm travelling a tonne and I'm stressed and my traumas are creeping up and I have way too much going on and I'm letting everything get to me, I will stop with B vitamin. It's almost hyper-stimulating. And so see where you are.

Like, listen to your body and see where you're at and then see how you feel when you take a B vitamin. But always take it with food because you will get so nauseous if you don't.

[ANGELA FOSTER] (57:34 - 58:15)
Yes, that is so true. And sometimes, right, taking it like three times a week, I find, is a good balance. That's a good idea.

Not necessarily even every day. I think a really good place to close would be for a woman who is listening to this, who's kind of like a plus one of you in a way. She's got children, she's either running a business, leading a team, she's got a lot on and she's listened to everything we've been saying today and she's learned so much, but she wants to kind of think about what would be a place for me to start?

So if I'm focussing on my sleep, my healthy behaviours, my movement practises, my nutrition, how can I use some of the body by-products to increase my overall resilience and cellular health?

[JESSICA KANE] (58:15 - 59:30)
I will start with a very simple place. My husband put this package together. He said just put together the main products that started Body Bio in the first place.

Put them in a box, in a bundle that make it easy for people. You're going to take two caps a day and that is called Cell Essentials. It's PC, it's balanced oil, it's butyrate.

So you've got the brain, you've got the cells, you've got the gut. And then most recently we just added in Remineralise, which is 72 trace macro-micro minerals. And that is going to go in your water.

So you're going to put a couple drops in your water and you're going to use that water to take those pills. It's just an easy routine. I'm actually thinking about even putting it in like a daily sachet.

So you can just open that sachet and take it right from there. It's the best way to just start on the journey. Don't get overwhelmed with high doses.

Don't go crazy. Take that, see how you feel. If you feel really great in three months and you want to throw in a little bit more PC because you want to address one tweak of fatigue or of brain fog or be even more peak performance, then you can add in a little bit more PC.

But that four product group, I used to call it a trio, but it's not a trio, it's a quad. That quad of products is really the starting place for everybody.

[ANGELA FOSTER] (59:30 - 59:37)
So this is the PC, the balanced oil, the butyrate, and the Remineralise, best place to start.

[JESSICA KANE] (59:37 - 59:40)
Best place to start. Those are the things I take every single day.

[ANGELA FOSTER] (59:40 - 59:51)
We will link to that in the description with a discount code for our listeners, which would be amazing. And then if you're struggling with sleep, Calm would be the place to go.

[JESSICA KANE] (59:51 - 1:00:19)
So you've got self-essentials plus Calm. Yeah, absolutely. Especially for moms.

Moms, women, high-performing women, it's just... There's so much fascinating research on high-performing women and trauma as well. So like all of these things are linked.

And if we don't want to let go of all the things that we're doing, and we enjoy doing them and they give us and we're fulfilled in our life, you just want to optimise your health so that you feel really good doing them.

[ANGELA FOSTER] (1:00:20 - 1:00:41)
100%. And I think that's the thing, is it's not even that so many people are dealing with burnout. Actually, what they're dealing with is kind of capacity problems.

They're like, I want to live this life. I want to have fun. I want to spend time with my kids.

I want to be able to lead my team better and do all these amazing things and have fun at the same time. Is there anything, Jess, that I haven't asked you that we should have covered?

[JESSICA KANE] (1:00:41 - 1:00:49)
I've covered a lot. Yeah, I don't think so. I think we've covered a tonne.

I'm glad. This has been a really great conversation too, because I think we went in some really interesting ways for people.

[ANGELA FOSTER] (1:00:49 - 1:00:52)
Yeah, I think we did. It's been fun. Thank you so much for coming over.

[JESSICA KANE] (1:00:52 - 1:00:54)
I know you're flying back tomorrow. Thank you for having me.

[ANGELA FOSTER] (1:00:55 - 1:00:56)
It's been great to have you here.

If you're in midlife and doing everything right but still battling fatigue, brain fog or bloating, this episode will change how you think about why.
I'm joined by Jessica Kane, cellular health expert and co-owner of Body Bio, to explore how cell membrane health drives energy, hormone signalling, and gut function, and what you can actually do to improve them.

This is a grounded, science-backed conversation for women who want to feel like themselves again.

WHAT YOU’LL LEARN
• Why perimenopausal women feel tired even when they’re doing everything right
• What causes brain fog in midlife women and how to improve focus and mental clarity
• Why bloating gets worse in perimenopause
• How gut health affects hormones, mood and energy in women over 40
• How poor cellular health can make perimenopause symptoms worse
• Why HRT works for some women but not others
• How stress and cortisol affect weight gain, cravings and resilience in midlife
• What butyrate does for bloating, blood sugar and gut health
• How healthy fats support hormones, skin, brain health and energy in midlife