EP 464- How to Reverse Biological Age, Balance Hormones & Slow Down Ageing—The Power of Glycans for Women’s Health | Nikolina Lauc

High Performance Health Podcasts -464

How to Reverse Biological Age, Balance Hormones & Slow Down Ageing - The Power of Glycans for Women’s Health | Nikolina Lauc

In this groundbreaking episode, I sit down with Nikolina Lauc, CEO and co-founder of GlycanAge, to unpack the science behind one of the most accurate biological age tests available today. We explore how lifestyle, hormones, and stress directly impact your biological age

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Description

What if you could measure how fast your immune system is ageing—and actually reverse it? In this groundbreaking episode, I sit down with Nikolina Lauc, CEO and co-founder of GlycanAge, to unpack the science behind one of the most accurate biological age tests available today. We explore how lifestyle, hormones, and stress directly impact your biological age—and how you can use cutting-edge science to turn back the clock.

You'll discover how oestrogen therapy, moderate exercise, and even small tweaks like swapping HIIT for yoga could potentially lower your biological age by up to 15 years. Plus, I share my personal GlycanAge results and the exact changes I'm making to optimise my health span. If you’re serious about proactive, data-driven health, this is a must-listen!

Key Takeaways

Glycans as Aging Markers: Glycans reflect the state of your immune system and offer early warning signs for chronic disease years before symptoms appear.

Men vs Women’s Aging Patterns: Women experience a rapid biological ageing spike during perimenopause and menopause linked to oestrogen decline.

Impact of Stress on Aging: Chronic psychological stress can accelerate biological ageing by up to 15 years—more than menopause itself.

Hormone Therapy Benefits: Starting oestrogen therapy around menopause can lower biological age by up to 10 years and reduce all-cause mortality by 40%.

Exercise Personalisation Matters: Moderate exercise supports longevity, but overtraining—especially in women—can accelerate ageing.

Lifestyle Tweaks Make a Big Difference: Small changes, like replacing high-intensity workouts with yoga, reduced one client's biological age by 15 years in 12 weeks.

Supplements and GlycanAge: NAD+ boosters and omega-3 enriched foods show promising effects, but personalised interventions work best.

Timestamps and Key Topics

0:00 - Introduction
1:26 - What are glycans and how they influence ageing
5:23 - Glycans vs telomere and epigenetic tests (accuracy differences)
10:57 - Problems with biological age testing noise
14:41 - The role of hormones in biological ageing
18:30 - How fast lifestyle changes can impact your biological age
22:57 - Why fasting and overtraining may hurt women’s health
27:11 - Personalising exercise to slow ageing
34:00 - Case study: How swapping HIIT for yoga reversed 15 years of biological ageing
40:18 - Angela’s personal GlycanAge test results
48:07 - How often you should test and what to change first
53:06 - The connection between sleep and your immune age

High
Performance
Health

The High-Performance Health Podcast is all about optimising your body, mind and lifestyle for high performance.

Packed full of actionable insights, strategies, bio hacks, lifestyle hacks, mindset strategies and expert performance advice, Angela Foster is on a mission to optimise your human potential. Featuring interviews with some of the top experts on the planet in the fields of health, performance and business, this show aims to inspire, educate and empower you to live an energetic, healthful and limitless life.

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A BIG thank you to our sponsors who make the show possible:

Supercharge your energy and upgrade your mitochondria with Mitopure - go to timeline.com/angela and enter code ANGELA to save 10%

Target 9 out of the 12 Hallmarks of Aging with Oxford Healthspan Primeadine - and use code ANGELA to save 15%

Test your biological age and gain powerful insights into your longevity and health at www.glycanage.com - use code ANGELA15 for your exclusive listener discount

Come join us inside the High Performance Health Collective—your space to learn how to work with your female physiology to live longer, stronger, and more energised—with a bonus peek into my private biological age consult to show you exactly how I’m reversing the clock - angelafosterperformance.com/hph-collective

About the Guest

Nikolina Lauc is the CEO and Co-founder of GlycanAge, a leading startup in the health-tech and longevity space who's technology was developed over 20 years of research supported by 40 million in European grant funding. Utilizing the largest proprietary dataset of human glycome, GlycanAge is pioneering advanced blood biomarkers for the prediction of age-related diseases.

Recently raising a $3.7 million seed round, the company is endorsed by Hub71, Mubadala's accelerator program. Nikolina is a serial entrepreneur with proven experience in scaling startups and leading growing teams. A Draper University alumna and Foresight Institute fellow, last year Nikolina was also recognized as the Entrepreneur of the Year 2023 in Croatia.

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About Angela

Angela Foster is an award winning Nutritionist, Health & Performance Coach, Keynote Speaker and Host of The High Performance Health Podcast.

A former corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela regularly gives keynotes to large fitness, health and wellness events including the Health Optimisation summit, The Biohacker summit, Dragonfly live, Elevate Fitness conference and Gaia TV. She also delivers Health Optimisation and Performance Workshops to large multinational corporations and senior leaders with a strong focus on women’s health and burnout prevention.

Angela is also the creator of BioSyncing® a blueprint for high performing women who want to ditch burnout, harmonise their hormones and elevate their life.